Cancer-miRNA
Regulatory Network
Compendium of
miRNA Target Genes
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HSCC Head-Neck Chung Cluster Number 11 (6627 genes)
This page contains all miRNA mediated regulation and functional enrichment for HSCC Head-Neck Chung cluster number 11. Information about head and neck cancer can be found on Wikipedia, and further information about the "HSCC Head-Neck Chung" dataset can be found in Chung et al., 2004.
Inferred miRNA Mediated Regulation
Weeder-miRvestigator PITA TargetScan
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Gene Ontology Enrichment
GO ID GO Term Annotated Genes in Cluster
GO:0000003 reproduction 475
GO:0000075 cell cycle checkpoint 130
GO:0000082 G1/S transition of mitotic cell cycle 118
GO:0000084 S phase of mitotic cell cycle 94
GO:0000216 M/G1 transition of mitotic cell cycle 61
GO:0000375 RNA splicing, via transesterification reactions 96
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 93
GO:0000398 nuclear mRNA splicing, via spliceosome 93
GO:0000722 telomere maintenance via recombination 17
GO:0001701 in utero embryonic development 128
GO:0001775 cell activation 351
GO:0002376 immune system process 714
GO:0002684 positive regulation of immune system process 240
GO:0002694 regulation of leukocyte activation 127
GO:0003012 muscle system process 145
GO:0003013 circulatory system process 154
GO:0003015 heart process 66
GO:0003018 vascular process in circulatory system 63
GO:0005975 carbohydrate metabolic process 316
GO:0006066 alcohol metabolic process 283
GO:0006082 organic acid metabolic process 419
GO:0006091 generation of precursor metabolites and energy 247
GO:0006098 pentose-phosphate shunt 10
GO:0006119 oxidative phosphorylation 39
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 25
GO:0006271 DNA strand elongation involved in DNA replication 22
GO:0006283 transcription-coupled nucleotide-excision repair 29
GO:0006312 mitotic recombination 25
GO:0006353 transcription termination, DNA-dependent 44
GO:0006354 transcription elongation, DNA-dependent 51
GO:0006366 transcription from RNA polymerase II promoter 542
GO:0006368 transcription elongation from RNA polymerase II promoter 41
GO:0006370 mRNA capping 21
GO:0006415 translational termination 54
GO:0006457 protein folding 113
GO:0006461 protein complex assembly 310
GO:0006464 protein modification process 1071
GO:0006468 protein phosphorylation 571
GO:0006508 proteolysis 430
GO:0006511 ubiquitin-dependent protein catabolic process 176
GO:0006520 cellular amino acid metabolic process 201
GO:0006521 regulation of cellular amino acid metabolic process 38
GO:0006605 protein targeting 164
GO:0006629 lipid metabolic process 488
GO:0006662 glycerol ether metabolic process 55
GO:0006694 steroid biosynthetic process 85
GO:0006702 androgen biosynthetic process 10
GO:0006720 isoprenoid metabolic process 37
GO:0006733 oxidoreduction coenzyme metabolic process 32
GO:0006739 NADP metabolic process 16
GO:0006740 NADPH regeneration 11
GO:0006778 porphyrin metabolic process 26
GO:0006793 phosphorus metabolic process 718
GO:0006796 phosphate metabolic process 718
GO:0006810 transport 1466
GO:0006873 cellular ion homeostasis 245
GO:0006886 intracellular protein transport 253
GO:0006915 apoptosis 691
GO:0006917 induction of apoptosis 224
GO:0006928 cellular component movement 372
GO:0006935 chemotaxis 295
GO:0006936 muscle contraction 136
GO:0006950 response to stress 1284
GO:0006952 defense response 454
GO:0006955 immune response 471
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 45
GO:0007154 cell communication 886
GO:0007165 signal transduction 1766
GO:0007166 cell surface receptor linked signaling pathway 964
GO:0007167 enzyme linked receptor protein signaling pathway 427
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 333
GO:0007220 Notch receptor processing 13
GO:0007264 small GTPase mediated signal transduction 288
GO:0007267 cell-cell signaling 486
GO:0007411 axon guidance 195
GO:0007584 response to nutrient 107
GO:0007586 digestion 60
GO:0007597 blood coagulation, intrinsic pathway 14
GO:0007610 behavior 197
GO:0008015 blood circulation 154
GO:0008104 protein localization 562
GO:0008152 metabolic process 3943
GO:0008202 steroid metabolic process 162
GO:0008203 cholesterol metabolic process 69
GO:0008283 cell proliferation 669
GO:0008284 positive regulation of cell proliferation 272
GO:0008286 insulin receptor signaling pathway 95
GO:0008610 lipid biosynthetic process 211
GO:0008645 hexose transport 62
GO:0009056 catabolic process 729
GO:0009057 macromolecule catabolic process 346
GO:0009060 aerobic respiration 27
GO:0009308 amine metabolic process 267
GO:0009408 response to heat 39
GO:0009452 RNA capping 21
GO:0009605 response to external stimulus 561
GO:0009607 response to biotic stimulus 249
GO:0009611 response to wounding 508
GO:0009615 response to virus 104
GO:0009628 response to abiotic stimulus 225
GO:0009636 response to toxin 49
GO:0009719 response to endogenous stimulus 369
GO:0009725 response to hormone stimulus 334
GO:0009891 positive regulation of biosynthetic process 430
GO:0009893 positive regulation of metabolic process 624
GO:0009894 regulation of catabolic process 165
GO:0009896 positive regulation of catabolic process 52
GO:0009952 anterior/posterior pattern formation 80
GO:0009987 cellular process 5404
GO:0009991 response to extracellular stimulus 167
GO:0010033 response to organic substance 660
GO:0010243 response to organic nitrogen 57
GO:0010466 negative regulation of peptidase activity 25
GO:0010498 proteasomal protein catabolic process 115
GO:0010604 positive regulation of macromolecule metabolic process 580
GO:0010817 regulation of hormone levels 176
GO:0010827 regulation of glucose transport 47
GO:0010833 telomere maintenance via telomere lengthening 25
GO:0012501 programmed cell death 696
GO:0012502 induction of programmed cell death 225
GO:0014075 response to amine stimulus 38
GO:0015031 protein transport 463
GO:0015749 monosaccharide transport 62
GO:0015758 glucose transport 62
GO:0015980 energy derivation by oxidation of organic compounds 179
GO:0016032 viral reproduction 249
GO:0016043 cellular component organization 1649
GO:0016053 organic acid biosynthetic process 121
GO:0016125 sterol metabolic process 72
GO:0016310 phosphorylation 640
GO:0016477 cell migration 303
GO:0019058 viral infectious cycle 122
GO:0019080 viral genome expression 85
GO:0019083 viral transcription 85
GO:0019362 pyridine nucleotide metabolic process 29
GO:0019538 protein metabolic process 1636
GO:0019725 cellular homeostasis 295
GO:0019752 carboxylic acid metabolic process 408
GO:0019941 modification-dependent protein catabolic process 181
GO:0022403 cell cycle phase 372
GO:0022415 viral reproductive process 133
GO:0022607 cellular component assembly 577
GO:0022616 DNA strand elongation 23
GO:0022900 electron transport chain 82
GO:0022904 respiratory electron transport chain 66
GO:0030163 protein catabolic process 226
GO:0030500 regulation of bone mineralization 25
GO:0031018 endocrine pancreas development 62
GO:0031099 regeneration 63
GO:0031100 organ regeneration 28
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 60
GO:0031325 positive regulation of cellular metabolic process 591
GO:0031328 positive regulation of cellular biosynthetic process 422
GO:0031570 DNA integrity checkpoint 80
GO:0031667 response to nutrient levels 152
GO:0031960 response to corticosteroid stimulus 67
GO:0032201 telomere maintenance via semi-conservative replication 19
GO:0032268 regulation of cellular protein metabolic process 493
GO:0032502 developmental process 1725
GO:0032570 response to progesterone stimulus 18
GO:0032787 monocarboxylic acid metabolic process 194
GO:0032870 cellular response to hormone stimulus 176
GO:0032879 regulation of localization 473
GO:0033013 tetrapyrrole metabolic process 26
GO:0033036 macromolecule localization 671
GO:0033238 regulation of cellular amine metabolic process 43
GO:0033273 response to vitamin 68
GO:0033554 cellular response to stress 484
GO:0034370 triglyceride-rich lipoprotein particle remodeling 9
GO:0034372 very-low-density lipoprotein particle remodeling 9
GO:0034613 cellular protein localization 306
GO:0034621 cellular macromolecular complex subunit organization 295
GO:0034622 cellular macromolecular complex assembly 218
GO:0035150 regulation of tube size 56
GO:0035270 endocrine system development 97
GO:0040011 locomotion 526
GO:0042060 wound healing 326
GO:0042110 T cell activation 142
GO:0042127 regulation of cell proliferation 482
GO:0042221 response to chemical stimulus 1193
GO:0042330 taxis 295
GO:0042440 pigment metabolic process 39
GO:0042445 hormone metabolic process 99
GO:0042493 response to drug 174
GO:0042592 homeostatic process 482
GO:0042773 ATP synthesis coupled electron transport 35
GO:0042775 mitochondrial ATP synthesis coupled electron transport 35
GO:0042981 regulation of apoptosis 563
GO:0043065 positive regulation of apoptosis 298
GO:0043067 regulation of programmed cell death 567
GO:0043068 positive regulation of programmed cell death 301
GO:0043085 positive regulation of catalytic activity 360
GO:0043086 negative regulation of catalytic activity 186
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 112
GO:0043170 macromolecule metabolic process 2940
GO:0043266 regulation of potassium ion transport 11
GO:0043412 macromolecule modification 1092
GO:0043434 response to peptide hormone stimulus 203
GO:0043632 modification-dependent macromolecule catabolic process 181
GO:0043691 reverse cholesterol transport 13
GO:0043933 macromolecular complex subunit organization 480
GO:0044057 regulation of system process 189
GO:0044237 cellular metabolic process 3554
GO:0044238 primary metabolic process 3600
GO:0044246 regulation of multicellular organismal metabolic process 14
GO:0044248 cellular catabolic process 589
GO:0044255 cellular lipid metabolic process 322
GO:0044257 cellular protein catabolic process 191
GO:0044260 cellular macromolecule metabolic process 2676
GO:0044265 cellular macromolecule catabolic process 276
GO:0044267 cellular protein metabolic process 1414
GO:0044419 interspecies interaction between organisms 215
GO:0045184 establishment of protein localization 475
GO:0045321 leukocyte activation 223
GO:0045333 cellular respiration 91
GO:0046394 carboxylic acid biosynthetic process 121
GO:0046627 negative regulation of insulin receptor signaling pathway 14
GO:0046649 lymphocyte activation 191
GO:0046782 regulation of viral transcription 37
GO:0046907 intracellular transport 414
GO:0048011 nerve growth factor receptor signaling pathway 141
GO:0048518 positive regulation of biological process 1355
GO:0048519 negative regulation of biological process 1177
GO:0048522 positive regulation of cellular process 1223
GO:0048523 negative regulation of cellular process 1075
GO:0048545 response to steroid hormone stimulus 144
GO:0048731 system development 1367
GO:0048856 anatomical structure development 1490
GO:0048870 cell motility 316
GO:0048878 chemical homeostasis 329
GO:0050434 positive regulation of viral transcription 32
GO:0050778 positive regulation of immune response 159
GO:0050789 regulation of biological process 3382
GO:0050790 regulation of catalytic activity 542
GO:0050792 regulation of viral reproduction 44
GO:0050794 regulation of cellular process 3202
GO:0050801 ion homeostasis 264
GO:0050865 regulation of cell activation 134
GO:0050878 regulation of body fluid levels 314
GO:0050880 regulation of blood vessel size 56
GO:0050892 intestinal absorption 15
GO:0050896 response to stimulus 2863
GO:0050900 leukocyte migration 107
GO:0051049 regulation of transport 343
GO:0051050 positive regulation of transport 171
GO:0051179 localization 1740
GO:0051186 cofactor metabolic process 124
GO:0051187 cofactor catabolic process 23
GO:0051234 establishment of localization 1485
GO:0051239 regulation of multicellular organismal process 626
GO:0051241 negative regulation of multicellular organismal process 135
GO:0051246 regulation of protein metabolic process 539
GO:0051259 protein oligomerization 117
GO:0051270 regulation of cellular component movement 151
GO:0051320 S phase 98
GO:0051325 interphase 206
GO:0051329 interphase of mitotic cell cycle 201
GO:0051340 regulation of ligase activity 68
GO:0051351 positive regulation of ligase activity 57
GO:0051352 negative regulation of ligase activity 50
GO:0051384 response to glucocorticoid stimulus 65
GO:0051385 response to mineralocorticoid stimulus 16
GO:0051412 response to corticosterone stimulus 13
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 47
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 50
GO:0051438 regulation of ubiquitin-protein ligase activity 66
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 55
GO:0051443 positive regulation of ubiquitin-protein ligase activity 55
GO:0051444 negative regulation of ubiquitin-protein ligase activity 50
GO:0051603 proteolysis involved in cellular protein catabolic process 190
GO:0051605 protein maturation by peptide bond cleavage 37
GO:0051641 cellular localization 730
GO:0051649 establishment of localization in cell 666
GO:0051674 localization of cell 316
GO:0051704 multi-organism process 454
GO:0051716 cellular response to stimulus 2109
GO:0051789 response to protein stimulus 75
GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction 20
GO:0051917 regulation of fibrinolysis 11
GO:0051969 regulation of transmission of nerve impulse 86
GO:0055080 cation homeostasis 189
GO:0055114 oxidation-reduction process 473
GO:0060047 heart contraction 66
GO:0060334 regulation of interferon-gamma-mediated signaling pathway 14
GO:0065003 macromolecular complex assembly 396
GO:0065007 biological regulation 3626
GO:0065008 regulation of biological quality 1159
GO:0065009 regulation of molecular function 644
GO:0070167 regulation of biomineral tissue development 27
GO:0070271 protein complex biogenesis 311
Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations
miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value

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